DAPTOMYCIN
Δαπτομυκίνη
Daptomycin is a lipopeptide antibiotic that kills susceptible gram positive bacteria by disrupting their membrane potential. It is a naturally-occurring compound found in the soil bacterium …
Φαρμακολογικό Προφίλ
Περιγραφή & Ένδειξη
Daptomycin is a lipopeptide antibiotic that kills susceptible gram positive bacteria by disrupting their membrane potential. It is a naturally-occurring compound found in the soil bacterium <i>Streptomyces roseosporus</i>. Antibiotics are used in the treatment of infections caused by bacteria. They work by killing bacteria or preventing their growth. Daptomycin will not work for colds, flu, or other virus infections. It was approved in September 2003 for the treatment of complicated skin and soft tissue infections. It has a safety profile similar to other agents commonly administered to treat gram-positive infections.
Κύρια Ένδειξη
Χρόνος Ημιζωής
7 days
Σύνδεση Πρωτεϊνών
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Μηχανισμός Δράσης
Daptomycin appears to bind or insert into the outer membrane of gram positive bacteria. The binding and integration of daptomycin into the cell …
Οδός Αποβολής
Daptomycin is excreted primarily by the kidney. In a mass balance study of 5 healthy subjects using radiolabeled daptomycin, approximately 78% of …
Όγκος Κατανομής
* 0.1 L/Kg [healthy adult subjects]
Κατηγορίες ATC
Βρείτε τη δραστική μέσα από τις αντίστοιχες κατηγορίες ATC level 5.
Διαθέσιμα Σκευάσματα
Εγκεκριμένα φαρμακευτικά σκευάσματα που περιέχουν DAPTOMYCIN.
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